Scientific litterature’s corner


Here is where you’ll find our favorite publications of the month…

 

Innovative pharmaceutical approaches for the management of inner ear disorders

UM Musazzi, S Franzé, F Cilurzo – Drug Delivery and Translational Research, 2017

 

Biomarkers for Hearing Dysfunction: Facts and Outlook

L Rüttiger, U Zimmermann, M Knipper – ORL, 2017

 

Previous months:

 

 

Transient auditory nerve demyelination as a new mechanism for hidden hearing loss

Guoqiang Wan & Gabriel Corfas, DOI: 10.1038/ncomms14487

 

Cochlear synaptopathy in acquired sensorineural hearing loss: Manifestations and mechanisms

M. Charles Liberman a, b, Sharon G. Kujawa

 

Cochlear hair cell regeneration after noise-induced hearing loss: Does regeneration follow development?

Fei Zheng, Jian Zuo

 

Cellular Mechanism of noise-induced hearing loss

A. Kurabi et al., Hearing Research, 2 December 2016

 

Effects of sodium thiosulfate versus observation on development of cisplatin-induced hearing loss in children with cancer (ACCL0431): a multicentre, randomised, controlled, open-label, phase 3 trial

D. R. Freyer et al., The Lancet Oncology, 30 November 2016, DOI: http://dx.doi.org/10.1016/S1470-2045(16)30625-8

 

Auditory Neuropathy – neural and synaptic mechanism

Moser & Starr, Nature Review, March 2016, doi:10.1038/nrneurol.2016.10

 

A comprehensive map of molecular drug targets

R. Santoset al., Nature Reviews Drug Discovery, 02 December 2016, doi:10.1038/nrd.2016.230

 

 

Can Animal Models Contribute to Understanding Tinnitus Heterogeneity in Humans?

Jos J. Eggermont, Frontiers in Aging Neurosciences, REVIEW, 14 November 2016, doi: 10.3389/fnagi.2016.00265

 

First hearing-disorder drugs stumble Clinical trial failures of two drugs for hearing loss and tinnitus underscore pitfalls for a nascent area of drug development, but lessons learned may help in navigating the uncharted path to approval

K. Kingwell, Nature Reviews Drug Discovery, 3 Nov 2016; doi:10.1038/nrd.2016.222

 

Glutamate receptor antagonists for tinnitus

Imsuwansri T, et al., Cochrane Database of Systematic Reviews 2016, Issue 10. Art. No.: CD012391, DOI: 10.1002/14651858.CD012391.

 

Role of antioxidants in prevention of age-related hearing loss: a review of literature

Elham Tavanai E., Mohammadkhani G., November 2016, Eur Arch Otorhinolaryngol, DOI 10.1007/s00405-016-4378-6