{"id":13680,"date":"2025-05-20T13:16:38","date_gmt":"2025-05-20T11:16:38","guid":{"rendered":"https:\/\/www.cilcare.com\/?p=13680"},"modified":"2025-05-21T11:21:10","modified_gmt":"2025-05-21T09:21:10","slug":"cilcare-and-cbset-publish-white-paper-on-gene-therapy-for-hearing-loss-in-world-pharma-today","status":"publish","type":"post","link":"https:\/\/www.cilcare.com\/jp\/2025\/05\/20\/cilcare-and-cbset-publish-white-paper-on-gene-therapy-for-hearing-loss-in-world-pharma-today\/","title":{"rendered":"Cilcare and CBSET publish White Paper on gene therapy for hearing loss in World Pharma Today"},"content":{"rendered":"<p><strong>We are pleased to announce the publication of a new white paper co-authored by <strong>Cilcare<\/strong> \u306e\u4e88\u9632\u304a\u3088\u3073\u6cbb\u7642\u3092\u76ee\u7684\u3068\u3057\u305f\u9769\u65b0\u7684\u306a\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u3092\u652f\u63f4\u3057\u3066\u3044\u307e\u3059\u3002 <strong><a href=\"https:\/\/cbset.com\/\">CBSET<\/a><\/strong>, featured in <em><a href=\"https:\/\/www.worldpharmatoday.com\/\">World Pharma Today<\/a><\/em>, titled:<\/strong> <strong>&#8220;Gene Therapy for Hearing Loss: A Translational Development Roadmap&#8221;<\/strong><\/p>\n\n\n\n<p>Authored by Lise Byelyayeva (Cilcare) and Ellie Khadir (CBSET), this article outlines a strategic, step-by-step roadmap for translating gene therapy research into clinical treatments for hearing disorders\u2014an area that, despite major advances in gene therapy, still lacks approved therapies.<\/p>\n\n\n\n<p>The paper highlights the unique challenges of developing gene therapies for inner ear indications and offers a roadmap to address scientific, regulatory, and translational hurdles. It also includes an overview of current clinical trials targeting Otoferlin-related hearing loss, illustrating real-world progress.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Key topics include<\/strong>:<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Vector selection and delivery routes<\/strong> for inner ear gene therapy<\/li>\n\n\n\n<li><strong>Surgical techniques<\/strong> for preserving auditory function during vector administration<\/li>\n\n\n\n<li><strong>Preclinical models<\/strong> \u306e\u4e88\u9632\u304a\u3088\u3073\u6cbb\u7642\u3092\u76ee\u7684\u3068\u3057\u305f\u9769\u65b0\u7684\u306a\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u3092\u652f\u63f4\u3057\u3066\u3044\u307e\u3059\u3002 <strong>assessements<\/strong><\/li>\n\n\n\n<li>Clinical trials designs and <strong>outcome measures<\/strong> for early-stage studies<\/li>\n\n\n\n<li><strong>Translational &amp; regulatory strategies<\/strong> to bridge the gap between discovery and clinical development<\/li>\n<\/ul>\n\n\n\n<p><strong>Read the full article here<\/strong>: <a href=\"https:\/\/www.worldpharmatoday.com\/articles\/gene-therapy-for-hearing-loss-a-translational-development-roadmap\/ \">https:\/\/www.worldpharmatoday.com\/articles\/gene-therapy-for-hearing-loss-a-translational-development-roadmap\/ <\/a><\/p>\n\n\n\n<p>This publication further reinforces Cilcare-CBSET\u2019s commitment to advancing breakthrough therapies for hearing loss and supporting our partners through every step of the development journey.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.cilcare.com\/wp-content\/uploads\/2025\/05\/GeneTherapy-WPTarticle-print.pdf\"><strong>Download full article<\/strong><\/a><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p class=\"has-text-align-center\"><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>We are pleased to announce the publication of a new white paper co-authored by Cilcare and CBSET, featured in World Pharma Today, titled: &#8220;Gene Therapy for Hearing Loss: A Translational Development Roadmap&#8221; Authored by Lise Byelyayeva (Cilcare) and Ellie Khadir (CBSET), this article outlines a strategic, step-by-step roadmap for translating gene therapy research into clinical treatments for hearing disorders\u2014an area that, despite major advances in gene therapy, still lacks approved therapies. The paper highlights the unique challenges of developing gene therapies for inner ear indications and offers a roadmap to address scientific, regulatory, and translational hurdles. It also includes an overview of current clinical trials targeting Otoferlin-related hearing loss, illustrating [&hellip;]<\/p>","protected":false},"author":6,"featured_media":13685,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[110],"tags":[134],"class_list":["post-13680","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-cilcare-launches-a-new-study-to-explore-hearing-in-patients-with-early-stage-neurodegenerative-diseases-and-identify-new-auditory-biomarkers","entry","has-media"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.3.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cilcare and CBSET publish White Paper on gene therapy for hearing loss in World Pharma Today - Cilcare<\/title>\n<meta name=\"description\" content=\"\u20ac40 million series A completed to accelerate development of innovative treatments for early hearing loss\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cilcare.com\/jp\/2025\/05\/20\/cilcare-and-cbset-publish-white-paper-on-gene-therapy-for-hearing-loss-in-world-pharma-today\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cilcare and CBSET publish White Paper on gene therapy for hearing loss in World Pharma Today - 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