human hearing measurements

At Cilcare, we specialize in advancing clinical auditory biomarker research to support the development of innovative therapies for hearing disorders, ototoxicity, and a range of conditions linked to auditory dysfunction such as neurodegenerative disorders, inflammatory diseases, and rare diseases. Our expertise in auditory biomarkers offers pharmaceutical, biotech, medtech companies, and academic researchers the tools and insights needed to accelerate their clinical trials and therapeutic developments.

human hearing assessment

Cilcare’s clinical expert team specializes in advanced human hearing measurements, utilizing state-of-the-art technologies and methodologies to assess auditory function in clinical settings. We offer tests such as tympanometry, acoustic reflex thresholds determinations, otoacoustic emissions (OAE), audiometry (pure-tone both air and bone conduction, speech recognition in quiet and in-noise)  and electrophysiology assessments to evaluate hearing performance in a wide range of populations, from healthy individuals to patients with hearing disorders. Our comprehensive approach enhances patient selection, helps identify difficult-to-diagnose conditions like cochlear synaptopathy, tracks disease progression, and evaluates treatment efficacy in clinical trials.

auditory biomarkers in clinical trials

Clinical auditory biomarkers are measurable indicators that provide objective data on auditory function, allowing for early diagnosis, disease monitoring, and more precise evaluation of treatment efficacy. These biomarkers are essential for improving patient selection, stratification, and response assessment in clinical studies targeting hearing loss and related conditions.

  • Patient Stratification & Monitoring: Cilcare leverages auditory biomarkers for patient stratification, enabling more accurate categorization of patients based on disease characteristics or likelihood of responding to treatment.
  • Biomarker-Assisted Clinical Trials: Cilcare can provide consulting services to design and conduct clinical trials that incorporate auditory biomarkers to improve patient selection, monitor disease progression, and assess the efficacy of drugs, devices, or biotherapies.
  • End-Point Evaluation & data analytics: Cilcare provides expert support in defining and applying objective, measurable endpoints for clinical trials. By leveraging advanced AI-driven data analytics, we help clients analyze large datasets, identify patterns, correlations, and predictive models based on auditory biomarker data. Our real-time monitoring analytics enable ongoing analysis during trials, supporting adaptive trial designs and facilitating data-driven, real-time decision-making.