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MAKING HEARING A PRIORITY
CILcare is the world’s leading R&D services company committed to making hearing a priority. Take an in-depth look at how we can support your R&D program to prevent and treat ear disorders.
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We are excited to announce that CILcare has released a new publication entitled, "Impulse Noise Induced Hidden Hearing Loss, Hair Cell Ciliary Changes and Oxidative Stress in Mice", in the journal Antioxidants, special issue "Oxidative Stress and Inflammation in...
We are pleased to announce that CILcare and its partner CBSET are organizing a workshop that will gather renowned experts in the field of inner ear diseases. Recent advances in understanding the mechanisms involved in inner ear diseases have accelerated the...
CILcare is pleased to announce that our Global Head of R&D Operations Management, Aurore Marie, will present the latest advances on ototoxicity during the CBSET Talking Tox Webinar as part of ACT's 42nd virtual annual meeting. We are also thrilled to announce the...
Pharma / Biotech
CILcare, the world leading CRO dedicating to ear disorders
Because research & development in hearing is as fascinating as it is complex, preclinical studies require perfectly accurate and reproducible measures using state-of-the-art technology in acoustics and electrophysiology. CILcare’s core values lie in our validated and highly robust animal models, enabling us to deliver consistent and valid results.
Drawing from an extensive industrial background, we guide our partners from target identification to IND, and work closely together to advance auditory research and reach a common goal: serve patient population who need our help the most.
CILcare proposes services to develop innovative solutions for hearing loss, tinnitus, otitis, and ototoxicity
Drugs to treat Hearing Loss and Tinnitus
Drugs and Medical Devices to treat Otitis
Medications safe for the ear (absence of ototoxicity)
Regenerative Therapies: Gene and Cell Therapies
Implantable Drug Delivery Devices and Imaging
Hearing disorders: a high unmet medical need
young people at risk of hearing loss
Disabling hearing loss could affect 2.5 billion people globally by 2050 according to the WHO. In 2019, 1.6 billion people were affected. This alarming and rapidly growing prevalence mainly results from population growth and aging, modern lifestyles with excessive noise exposure, the intake of ototoxic drugs, and chronic ear infections.
Hearing loss has been ranked as the fourth highest cause of disability worldwide, higher than many other chronic diseases including diabetes, dementia, and chronic obstructive pulmonary disease. Deafness profoundly affects the quality of life of patients and is strongly linked to cognitive decline in the elderly. Unaddressed hearing loss costs countries an estimated US$ 1 trillion annually, therefore posing a significant issue to our health systems.
A hundred pharmaceutical and biotechnology companies and thousands of academics are contributing to scientific progress in the auditory field. Although no drugs have been approved by authorities to treat hearing loss and tinnitus yet, some actors are reporting promising scientific research results. These hold the promise of filling an unmet medical need and having transformative impacts on patient populations in the near future.
“CILcare is definitely more than a simple CRO! Following our work experience in PK/PD studies, CILcare now resonates as a trusted partner, fully committed to the success of their Sponsor’s assets. CILcare’s scientific expertise in the auditory system and neurosciences is no longer in doubt. The robustness of CILcare’s animal models, which highly mimic human ear disorders, gives us the confidence for translational success in clinical phases. It is always a pleasure to work with all the team members, they are very proactive, responsive, and dedicated to their customers.” Carmen Herrero, CSO, Spiral Therapeutics